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What is the Gateway Hypothesis The Gateway hypothesis states that there is a causal sequence through classes of drugs, whereby the use of less harmful substances is a risk factor for using harder drugs

Psychopharmacology (Berl) 2009

These studies show that immune cell responses are less affected by cMRTP aerosols than cigarette smoke, especially regarding their release of chemokines and cytokines such as IL-8 and TNF [76, 77]